Purpose:
The Papanicolaou stain, including EA-36, is widely used in cytology for the diagnosis of various conditions, including cervical cancer screening (Pap test or Pap smear).
Components:
The Papanicolaou stain typically involves a nuclear stain (hematoxylin) and one or more cytoplasmic counterstains, including EA-36.
Function of EA-36:
EA-36, along with other EA formulations (like EA-50 and EA-65), provides differential staining of the cytoplasm, allowing for better visualization of cellular structures and the differentiation of cell types.
Gynecological and Non-Gynecological Applications:
EA-36 is suitable for staining both gynecological (e.g., cervical and vaginal smears) and non-gynecological specimens (e.g., respiratory secretions, body fluids).
TM Media:
TM Media is a manufacturer of various microbiological and cytological products, including the Papanicolaou EA-36 stain.
Staining Results:
EA-36, as part of the Papanicolaou stain, can produce a range of colors in the cytoplasm, with the exact hues depending on the specific cell type and the other reagents used in the staining process. For example, some cells may appear orange, while others may be sky-blue or light green, depending on their state of keratinization.
Quality Control:
EA-36 is often quality controlled to ensure consistent and reproducible staining results.
