Double-frosted microscope slides are used in labs for labeling samples on both ends, which is ideal for handling larger specimens or for situations where multiple samples are prepared on a single slide. The frosted ends provide a writable surface resistant to common chemicals and stains, and some versions have a slightly rougher surface for better adhesion of delicate samples. These slides are commonly used in research and clinical settings, including histopathology, cytology, and hematology.